Searchable abstracts of presentations at key conferences in endocrinology

ea0059apw2.1 | Metabolites as hormones | SFEBES2018

Metabolic and microbial investigation of weight loss surgery

Li Jia Li , Ashrafian Hutan , Seyfried Florian , Holmes Elaine , Gooderham Nigel

Bariatric surgery, in particular, Roux-en-Y gastric bypass (RYGB), is the most effective treatment for morbid obesity. The restricted gastric capacity and reduced absorption of nutrients cannot account for all the metabolic benefit we observe post-operation. Therefore, we applied metabolic and microbial profiling approach to investigate the potential mechanisms of RYGB surgery. Metabolic profiling strategy is widely applied in the discovery and development of metabolic biomark...